What is Sildenafil?
Sildenafil is a medication used to treat erectile dysfunction. Erectile dysfunction is the inability to get and keep an erection in men. Erectile dysfunction, sometimes called impotence, has several causes. Causes of erectile dysfunction include heart disease, high blood pressure, diabetes, low testosterone, stress, depression, and most commonly due to a narrowing of the arteries that take blood to the penis.
What are The Benefits of Sildenafil?
Sildenafil works by preventing the action of a chemical in the body called Phosphodiesterase type 5. This helps relax and widen blood vessels to improve the flow of blood. In erectile dysfunction, Sildenafil improves the blood flow to the penis following sexual stimulation, and helps to maintain an erection. In a study published in the New England Journal of Medicine titled “Oral Sildenafil in the treatment of Erectile Dysfunction”, it was found that “For the men receiving 100 mg of sildenafil, the mean score for the question about achieving erections was 100 percent higher after treatment”. Not only does Sildenafil work, but it has also been found to have a low rate of adverse reactions. During a four year study titled “Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction” by the Multicenter Study Group published in the US National Library of Medicine, 979 men used sildenafil and only 37 had “adverse events that led to changes in dosing or to temporary or permanent discontinuation”. Most of the adverse effects that led to change were headache and flushing.
Sildenafil is also used to treat Pulmonary Arterial Hypertension. PAH is a type of high blood pressure that occurs between the heart and the lungs. When hypertension occurs
In the lungs, the heart must work harder to pump enough blood through the lungs. Sildenafil works by relaxing and dilating the blood vessels in the lungs and decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs which generally results in the ability to be more active. Howard C. Herrmann, MD published his findings on sildenafil for primary pulmonary hypertension and found that the ability to exercise, cardiac index, dyspnea, and fatigue all improved with the use of sildenafil.
What are The Side Effects of Sildenafil?
Sildenafil may cause drowsiness, dizziness, fainting, or blurred vision. These effects may be worse if you use it with alcohol or certain medicines. Use Sildenafil with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to the medication. Sildenafil should not be taken by people who take nitrates such as Nitroglycerin, as this may result in a severe and potentially fatal drop in blood pressure.